CAUTION AMERICAN CITIZEN, INFECTIOUS DISEASE DEVELOPING FAST!

Expansion of Emerging Infectious Disease Sooner

Antibiotics can be said that the most important progress in the history of modern medicine. It is estimated that deaths in the United States decreased by 220 per 100,000 with the introduction of sulfonamides and penicillin in the early antibiotic era.

Far exceeds the benefits to be gained with other medical advances in the last century. The main threat we now face is the increasing resistance to antibiotics, which endanger much of this progress. It must be recognized that the evolution of bacterial resistance can not be avoided. But the damage is highly promoted by the use of antibiotics. The problems faced was the resistance of microbial growth and as a result of the use and abuse of drugs, which have unintended consequences clearly more resistance.

In the past, antibiotic resistance is a challenge that is usually met by the development of new antibiotics, but newer problem is the pharmaceutical industry almost all interested in producing new drugs.

So, 1983-2010, U.S. Food and Drug Administration (FDA) approval of new antibiotics continues to decline, from 4 per year in the early 1980s to less than 1 antibiotic per year now.



Perhaps more important than the reduction of drugs to fight the bacterium is bacterial resistance and clinical effects. Infection Disease Society of America (IDSA) recognized this problem in 2004 with the creation of antibiotics Availability Task Force (AATF). This organization summarizes the issues in the relevant documents, beginning with "Bad Bugs, No Drugs," a review of interviews with executives from pharmaceutical companies that historically is the largest producer of antibiotics. their reasons for returning to the development of antibiotics is good business:

* Antibiotics are a short term drug which is usually consumed for 1-2 weeks, but agents on cardiovascular, rheumatologic, and neurological, consumed by patients for decades.
* Investment is needed to "bring the drug to kepasaran" estimated almost $ 1 billion, the possibility of "return on investment" to antibiotics is almost nil.
* We also heard: "If you develop a cure for resistant bacteria, the doctor tells you to reserve them for a relatively rare condition."
* Changes in the environment unpredictable and highly risky in clinical areas.

Pathogens of concern. Meanwhile, the organism of concern continue to grow in number. the main bacteria that is defined as "ESKAPE" microbes in reference to Enterobacter, Staphylococcus aureus, Klebsiella, Acinetobacter, Pseudomonas aeruginosa, and Enterococcus. Ten years ago, we witnessed the global spread of new strains of S. aureus containing the Panton-Valentine Leukocidin, referred to here as "USA 300 strain.

"It is dominating the attention to resistance to the" bad bugs, "but an even greater attention has recently been expressed about gram-negative bacilli, especially those producing carbapenemases. This includes Carbapenemase K. pneumoniae-producing Enterobacteriaceae that emerged in the United States began in the 2000s.

However, the most worrying of all has occurred recently in New Delhi-Metallo beta-lactamase (name of his town of origin) who first become infected patients hospitalized in New Delhi and then spread, first with a trip to England and then globally.

The organism is resistant to nearly all currently available antibiotics except for colistin and tigecycline.

The concern in the European health agencies have recently produced remarkable monograph with a comprehensive review at this time the development of new drugs for resistant bacteria.

They show that the last new class of drugs active against gram-. negative bacteria back almost 40 years! They also attempted to identify a new class of tight for gram-negative bacteria in development, including in-depth study on drug trials in 2 phases or more.

None required Historically, approximately 8 years of drug discovery to FDA approval showed that, even if now working aggressively and successfully, there is little possibility of a new drug discovered before 2015.

Public attention to the crisis of antibiotic resistance in the face of a relatively dry pipeline is a priority issue that suddenly withdrawn. On November 4, 2009, President Obama and Prime Minister of Sweden Fredrik Reinfeldt, who represented the European Union, formed the Transatlantic Task Force on Antibiotic Resistance (TATFAR) to provide engineering attacks against this issue by the United States and Europe. The other two relevant congressional requests have been proposed, including Senate Bill 2313: Strategies To Address Antibiotic Resistance (STAAR Act), and House bill 6331, largely designed to provide incentives for pharmaceutical companies to develop antibiotics.



In addition, the National Institute of Allergy and Infectious Diseases National Institutes of Health announced plans to build a collaborative network of academic centers to test new antibiotics and the issues that are relevant to antibiotic resistance.

Center for Disease Control and Prevention (CDC) announced "so smart about antibiotic program" to provide guidance, especially through the ministry of antibiotics, in increasing the use of the drugs we have today.

It should be noted that France, which has the highest rate of antibiotic use in the EU, addressing the perceived problems with the misuse of antibiotics is expensive and very ambitious campaign directed at both consumers and physicians. 5-year goal is to reduce the likelihood of prescribing antibiotics for viral respiratory tract infections by 25%. A recent report indicates that this goal is achieved.

For the United States, antibiotic resistance was responsible for nearly 100,000 deaths caused by hospital infections per year earned an annual cost estimated $ 23,000,000,000. This is clearly attracted the attention of the Centers for Medicare & Medicaid Services, in the hope that the misuse of antibiotics will lead to public reporting and financial penalties.

The conclusion is that resistance has now reached a stage of crisis, largely because of the lack of new antimicrobial agents to maintain the effectiveness of which has been enjoyed for more than 50 years. The good news is that the consensus has been reached that this is an important issue, although it was too late realized. Physicians should be aware of this issue and agreed to assist in efforts to maintain the current activity of drugs that are available through the conservation of antibiotics that are consistent with good practice.

GIANT FOSSIL IN BALI INDONESIA

Giant, whether myth or real? Apparently there are fossils of giant in BALI!

As a child we may often hear tales about the giants of our parents or at least once a giant fairy tale book.

Apparently all is not figment. Having already found a giant human skeleton which arises because gas exploration occurring in the deserts of Saudi Arabia.

Apart from the skeleton found in Saudi Arabia, many are also found in other giant skeletons in the world. Among others in Ireland, India, America, Fiji Japan, Turkey, South America etc.. This proves that the giant had ever lived on our earth is thousands of years ago.

National Archaeological Center research team has found ancient human migration paths in Lombok. BALI is the result of research findings for a week, 18 to 24 October 2003, in South Pelambik Village, Central Lombok, and North Sembalun Village, East Lombok.

Head of the Museum of West Nusa Tenggara Province Joko Prayitno, Saturday afternoon (1 / 11) explains, to a depth of two meters there is still evidence of millennia-old equipment that was found during the study. In fact, before Lombok otherwise not track them.

"It is proposed the excavation of the site, all the fossils found there," said Joko. According to him, who will perform excavation (archaeological excavations) is a joint team of the National Center for Archaeology and the Archaeological Institute of Denpasar.

National archaeological team led by three-person expert Jatmiko paleolithic, geology, paleontology, namely Thomas Sutikno, E. Revelation Saptomo, and Romania Lumban Gaul. This study is a continuation of the survey to clarify the findings of RP Soejono ever undertaken in 1987. Soejono find the tools of the past civilizations (paleolithic), of which the form of stone axes used to cut the animals and grow crops, as well as some that have been petrified wood fossils and geological outcrops and old. And the most excited, there are fossils of a giant!

With the discovery that equipment, is now archeological team will look for human skull fossil animals and GIANT. These findings may complement the Lombok tourism attraction. Special interest tourists, some of which arkologis from France, will make Lombok as a tourist destination.

ni after confirmed the findings of Lombok is an early human migration paths in the past. Currently, Gilimanuk Bali has become the object of experts from the French. "The findings are the main attraction of its own special interest tours the world," said Joko.

Secrets of Albert Einstein's Theory of Relativity II

Albert Einstein, no doubt, the greatest scientist of the 20th century. Scholars unparalleled throughout all ages. Included because the theory of "relativity" of his. Actually this theory is a theory linking the two to each other: the special theory of "relativity" which formulated in 1905 and the general theory of "relativity" which formulated in 1915, better known to the law of Einstein gravity. Both theories are very complicated, because it is not the place here to explain as it is, however rudimentary description of the problem of special relativity there is little mention. Proverb says, "everything is relative." Einstein's theory is not just chewing on that phrase that was almost boring. He is referring to an exact mathematical opinion about the scientific principles that actually relative. Essentially, subjective assessment of time and space depends on the adherent. Before Einstein, people generally believe that always there behind the subjective impression of absolute space and time that can be objectively measured with the equipment. Einstein's theories overturned by revolutionary scientific thinking by refusing the existence of the absolute time. The following example to illustrate just how radical his theory, he said he revolutionized how we think about space and time.

Imagine a spacecraft called the X-call it speed-sliding away from Earth at 100,000 miles per second. Speed is measured by observers, both located on the spacecraft X and in the earth, and measure them simultaneously. Meanwhile, a another spacecraft called the Y gliding rate in the same direction with the spacecraft X but with excessive speed. If an observer on earth measures the speed of the spacecraft Y, they knew that the plane was speeding away from Earth at a speed of 180,000 miles per second. Observers aboard the space Y will be similar conclusion.

Well, since both the spacecraft was moving in the same direction, it would appear that the speed difference between the two aircraft had 80,000 kilometers per second and faster aircraft that could not be moved away from the plane which is slower at this speed level.

However, taking into account Einstein's theory, if the observations were made from both spacecraft, they will agree that the distance between them increases in the level of the size of 100,000 kilometers per second, instead of 80,000 kilometers per second.

It appears this is impossible. It looks like a prank. Readers suspect smells as if there is deception. Predicting lest there are details hidden. In fact, absolutely not! This result has nothing to do with energy used to encourage them.

Nothing wrong observation. As a result, nothing less, equipment is damaged or twisted cable. Smooth, smooth, not misleading. According to Einstein, the results of the above conclusions were solely as a result of the true nature of space and time can be calculated through the velocity composition formula affairs.
10 ALBERT EINSTEIN atomic bomb inventor

atom bomb



Seems to be a virulence theory, and indeed many years away from the "theory of relativity" is like away from the hypothesis "ivory tower," as if that theory had no significance at all. Nobody, of course, does not make a mistake-until in 1945 when he swept the atomic bomb Hiroshima and Nagasaki. One of the conclusions "theory of relativity," Einstein is the matter and energy are in a sense be balanced with and the relationship between the two formulated as E = mc2. E shows the energy and m indicates the mass of the object, while c is the speed of light. Well, because c is the same with 180,000 kilometers per second (that is a very large number of digits) by itself c2 (which means cxc) karuan tepermanai just not large in number. As such means, although the conversion of a fraction of objects able to spend an enormous amount of energy.

People would not have known it could make an atom bomb or a nuclear energy center solely stick to the formula E = mc2. It should also be studied deeply, many people play an important role in the process of generating atomic energy. But, however, Einstein's contribution was not doubting mind again. No one is bickering in this matter. Furthermore, none other than Einstein the person who wrote a letter to President Roosevelt in 1939, indicating the opening of the possibility make atomic weapons and simultaneously emphasize the importance for the United States as soon as possible make the weapon before Germany preceded. The idea was then realize the "Manhattan Project" which could eventually create the first atomic bomb.

"The theory of special relativity" a warm inviting different opinions, but in one sense all agree, that theory is the most dubious idea that human beings ever formulated. However, everyone was fooled because "the theory of general relativity" Einstein is the starting point of another thought that the influence of gravity is not due to physical strength in the usual sense, but rather a result of the curved shape of space itself, an opinion which is very astonishing!

How can one measure the curvature of space?

Einstein is not just to develop a theoretical, but poured into the mathematical formulation of clear and obvious so that people can make real predictions and testable hypothesis. The next observation-and this is the most brilliant because it is done when the total solar eclipse, has repeatedly believed the truth because it coincides completely with what was said Einstein.

General theory of relativity stands apart in some respects with all scientific laws. First, Einstein did not formulate his theory on the basis of the experiments, but on the basics of symmetry and mathematical subtlety. In short based on a rational basis as usual habits of the Greek philosophers and scholars do middle century. This means, Einstein different ways with the method of modern scientists who hold empirically. However, the difference there is also: Greek thinkers in terms of beauty and symmetry craving never successfully manage and find a theory that is able to withstand the mechanical testing experiments are complicated-complicated, while Einstein could survive with the success of each trial. One result of this approach is that Einstein's general theory of relativity is considered a very beautiful, stylish, strong and intellectually satisfying all scientific theories.

The theory of general relativity is also in some ways stands separately. Most other scientific laws are only approximately valid. There are taxable in many ways, but not all. While the general theory of relativity, all knowledge, is completely acceptable without exception. There is no state of the unknown, both in terms of theoretical or experimental practice shows that predictions general theory of relativity applies only approximately. It could be experiments in the future ruin the good name of perfect results ever achieved by any theory, but insofar as the general theory of relativity, clearly remains the most reliable approach for every scientist in his efforts toward final truth.

Although Einstein was very popular with the "theory of relativity" him, the success of his work in other scientific fields also make it famous as a scientist in every facet. In fact, Einstein received the Nobel Prize for physics in particular because of his written thoughts reveal the effects of photo-electric effect, an important phenomenon which previously was a puzzle the scholars. In the work of Einstein's scientific papers that prove the existence of photons, or particles of light.
10 ALBERT EINSTEIN are mendiskusikn theory

EINSTEIN is OPINION theory



Old assumption by halting experiments say that light is composed of electro magnetic waves, and wave and particle are opposite concepts. While Einstein's hypothesis indicates a radical difference and very contrary to classical theories. Not only was the law of electric images shown to have important meaning in use, but the hypothesis about the photon have a major influence in the development of quantum theory (the hypothesis that in radiation, electron energy released is not continuous but in a certain amount) which is currently an integral part of that theory.

In terms of assessing the significance of Einstein, a comparison with the Isaac Newton is striking. Newton's theory is basically easy to understand, and his genius was shown in the beginning of the development. While the "theory of relativity," Einstein's very difficult to understand even by a careful explanation and caution. More-More complicated again if recapitulate the original! When some of the ideas clash with Newton's scientific ideas of his time, his theory was never looks faded or wavered in its establishment. On the contrary, "the theory of relativity" is full of contradictory things. This is part of the genius of Einstein that at the beginning, when the idea is still an untested hypothesis which has put forward a dozen years as a young man who was entirely unknown, he never let the contradictions that obviously there is and discard the theory. On the contrary in fact he very carefully and cautiously ponder continue until he is able to show that this contradiction is only on the birth of every problem when in fact it is always available to resolve this contradiction in a way that subtle yet clever and decisive.

Now, we consider Einstein's theory is essentially more "correct" than Newton's theory. If so the case why Einstein was placed more under the list of the order book level?

The reason for this is available. First, theories Newtonlah which is the foundation stone and cornerstone of modern science and technology. Without the work of Newton, we will not be watching today's modern technology. Instead of Einstein.

There is another factor that explains why Einstein's position in the order that the reader witnessed. In many ways, the development of an idea involves contributions of many people. This definitely does for instance in the history of socialism affairs, or in the development of electric and magnetic theory. Although Einstein was not 100% formulated "the theory of relativity" with his own brain, which most certainly does its share. It is fair to say that judging from the comparative importance of other ideas, theories of relativity are mainly derived from the creation of a, the genius and the topnotch, Einstein.

Einstein was born in 1879, in the city of Ulm, Germany. He entered college in Switzerland and became a Swiss citizen in 1900. In 1905 he received a doctorate from the University of Zurich but (strangely) can not be reached for an academic position at the time. In that year he also published a working paper concerning the "special relative," about the photo electric effect, and the theory of Brownian motion. Only in a few short years these working papers, particularly those involving relativity, has made him one of the most brilliant scientists and most original in the world. His theories are very controversial. There was no world except Darwin scientist has ever created a controversial situation like Einstein. Due to that, in 1913 he was appointed professor at the University of Berlin and at the same time as Director of the Institute of Physics "Kaiser Wilhelm" and become a member of the Prussian Academy of Sciences. These positions are not tied to freely devote all my time doing investigations, whenever he likes.

The German government does not regret Einstein's flush with the long line of special status because of exactly two years later, Einstein managed to formulate "a general theory of relativity," and in 1921 he received the Nobel Prize. Throughout the last half of his life, Einstein became a byword of the world, and almost certainly he was a famous scientist who was born into the world.

Because Einstein was a Jew, his life in Germany became unsafe so Hitler rose to power. In 1933 he moved to Princeton, New Jersey, United States, worked at the Institute of Advanced Studies and Higher in 1940 became U.S. citizen. Einstein's first marriage ended in divorce, only the second marriage just seem happy. Had two children, both boys. Einstein died in Princeton in 1955.

Einstein was always interested in the affairs of humanity the world around him and often expressed his political views. He is a steadfast fighter against the political system of tyranny, a staunch supporter of pacifist movement, and a steadfast supporter of Zionism. In terms of dress and social habits that he looked an individualistic. Like humor, simple and no strings violin talent. Newton's tomb inscription on the headstone that reads: "rejoice because the spirits of the abandoned ornamentation for humanity!" They are more subject to Einstein.

Beached Mermaid KUTA BALI

Mysterious mermaid found in the village of Pecatu, South Kuta, Bali, Indonesia. The discovery of this strange creature menarikperhatian many people, including citizens of foreign tourists in Bali and the State.

Mermaid, according to legend is a creature half human and half fish. Part keatasnya human body is a beautiful woman, complete with fantastic breasts and a very pretty face. While the bottom of a big fish.
This mysterious mermaid found in a similar grave mound by the officer in the Village area Pecatu, Kuta Bali, Indonesia. After further investigation it turns out his body shape and the DNA is similar to the MAN!
lifesavers. Mound itself in between the rocks, in the village of Pecatu, South Kuta Bali. If you're curious, please come to Bali.
The discovery took place on Friday (06/08). Residents around the scene immediately because it is believed that the mysterious object could lead to disaster. The Balinese believe strongly mystical, because they fear it being jinxed.
Not only mermaids, but found also 2 Jenglot on the discovery. It's so AMAZING.
Finally, by the chairman of the local custom, the mysterious creature floated back into the sea.
According to information, the discovery of three mysterious objects that began when officers lifesavers tirta tourism board (Balawista) perform the task of observing the state beach Labuan Sait.
Wayan Sober, chairman of the Task Force on the coast of Labuan

Sait said, while watching the beach, the officer suspected with a mound of soil in between the rocks that are similar to the grave.
"When the officer was found 3 to explore the mysterious creature by 40 centimeters tall, with long hair," says Wayan.
"Then the officer reported finding a mysterious creature that the Chairman of the local customs," he added.
After reporting the findings of the mysterious creature, Chairman of the Peoples concluded that 3 is a supernatural creature, the Mermaid and Jenglot.
"Chairman of the indigenous and community believe that at certain times miterius creatures that must be fed in the form of chicken or human blood," says Wayan.
Therefore consideration if not treated properly can cause becana and havoc, it was decided the three entities was washed away into the sea. Afraid to take RISK!
The three entities was floated back into the sea using boats. Community seyempat believe that the third creature had a mystical power and should be treated properly. However, if sold would bias wealthy, right?

JENGLOT JIMBARAN FOUND IN BALI INDONESIA

Tombs Jenglot Jimbaran Bali Indonesia was first discovered by Army officers Wista Pecatu Labuan Sait Jimbaran beach while being monitored from the top of the cliff, Friday, May 7, 2010. When turned to the left side, the officer was suspicious of the mysterious mound that turned out to be the tomb (grave)
Bali-reportase.blogspot.com again proclaim a major event, namely the discovery of small small things like humans, but like a rat size.

After the grave has been dug, a resident found three specimens in the form of a mermaid small size and long hair wrapped in white cloth and two more in the form Jenglot. Jenglot the cross-legged in a sleeping position and length of each about 40 centimeters (cm).
Meanwhile, in the vicinity of the location of the discovery of the tomb Jenglot Jimbaran Bali Indonesia fragrant smell that mingled smell of dead bodies.
Jenglot invention is of course make a scene and disturb residents tourists.



Is Jenglot? Really Jenglot there?
Jenglot is a strange phenomenon began to spread in the community BALI Indonesia in 1997an. Jenglot is an object / creature (I'm confused determine whether the object or creature) who form a small man with a body no more than 12 cm and his long hair, rare and stiff through the legs, and long fingernails.
Jenglot believed to society is as a person who has the magic of science in the past (maybe a hermit so) who died, but he was rejected by the earth, so that his body was not destroyed but shrunk into shapes like Jenglot. Means believed that "Jenglot it used to be a man" ...



If examined in terms of scientific, obviously there may be a phenomenon like this. The human body would decompose if buried in the soil. But in reality Jenglot have similar DNA to humans when tested in modern laboratories. Are you curious? Please come to Bala Wista Pecatu Labuan Sait Jimbaran Bali Indonesia. Jenglot still there, and is waiting for you!

Hacker Bali Ready Master the World!

Bali is now the center of world attention. On December 16 to 17 October 2010, has held Security Conference 2010 (IDSECCONF 2010) on the island of Bali. And some hackers can penetrate the defense Bali defense system the U.S.!

The event was adu dikes, alias the game "capture the flag", it will position the guards server as a keeper of the castle. To seize the flag of the fort, first conquered guardian.

The game was organized by STMIK hacker Bali, each participant may use any ability to break down servers jury.

What is the impact of this activity?



Apparently a number of observers of American computer security (FBI?) Have already seen signs of hackers Bali. Some of them want to try the defense system the U.S. banking security. And this is very interesting!

Actually, this year's conference theme is security in electronic transactions in banking and electronic payments. Various security issues and vulnerabilities in e-banking transactions and e-payment will be discussed. And this is closely connected with the hot issue in America.

The hackers Bali was sharpening ourselves to prove the sharpness of the science of hacking. And it's not kidding. They actually only to learn, but its ability is very wary of.

Hackers can melakukanbanyak hal.Bisa in and change the password your e-banking account, online stores can damage your back door can embed program (Trojan) to your computer remotely controlled, can steal personal data your computer and more.

Hacker in Bali are planning something. Beware ... beware!

UFO APPEARS IN BALI INDONESIA !

UFO crop circle trail in Sleman, Yogyakarta, 695 km from Bali Indonesia. According to the investigation, the arrival of UFOs to the area for the first time. And this raises a big question mark, why do UFOs come from?

According to some analysis of Bali, UFO comes associated with the eruption of Mount Merapi, a phenomenon some time ago. UFO very sensitive to radiation of the earth, and they immediately came to investigate what is happening around Bali and Yogyakarta them.



Symbols abandoned UFO SAME PERCIS with symbol has ever seen anywhere in the world, the crop circle. And babarapa time ago, the official Indonesian police have found the meaning behind the symbol UFO,

Indonesian Police increasingly convinced the mysterious symbol of Unidentified Flying Object (UFO) or known as crop circles in the rice fields in Sleman, Yogyakarta.

"Earlier we had checked in there at 17.00 pm and there was a giant round picture and have our photos. Hebohnya said residents had since morning," said police duty officer Berbah, Sleman, Yogyakarta, First Brigadier Kastono, told AFP on Sunday (23 / 1 / 2011).



Kastono said many local people who watch a unique symbol of the good from near and from the hill. Police also lowered its officials as a precaution. The symbol that looks good only if from afar, but did not draw if close.

"This afternoon we are just there because many residents. If it's quiet, the weather was too rainy," he explained.

Kastono then describes the weather conditions in the region these days is not good. But residents still believe the emblem is a symbol of a UFO landing from another planet.

"If the wind so I think difficult to form a symbol.'s Why people believe it is the symbol of a UFO," he concluded.

Some opinions began to arrive. Some say that man-made wish to seek popularity, but some are of the opinion that due to natural phenomena.

Apart from these two opinions, no one is close to scientific truth. Unless it's true UFO trail. Besides leaving the crop circles that can be understood in general, also because of the perfection of the left circle.

If humans, who can? Moreover, only in one night?